Synthesis and Biological Evaluation of Cinnamaldehyde Analogues for Anti-Arthritic Activity
نویسنده
چکیده
The present study is aimed to evaluate the anti-arthritic activity of novel Schiff bases of cinnamldehyde using in-vitro inhibition of protein denaturation model. All the compounds synthesized were characterized by running TLC, UV, IR & MS spectra. Diclofenac sodium was used as a standard drug for anti-arthritic activity. Results revealed that the derivative Cinnan 2 possessed significant anti-arthritic activity as compared to standard drug Diclofenac sodium. The remaining derivatives showed dose dependent activity.
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